| 品牌 | 其他品牌 | 貨號 | BFN60808857 |
|---|---|---|---|
| 規(guī)格 | T25培養(yǎng)瓶x1 1.5ml凍存管x2 | 供貨周期 | 現貨 |
| 主要用途 | 僅供科研 | 應用領域 | 醫(yī)療衛(wèi)生,生物產業(yè) |
細胞名稱 | 人肺腺癌細胞HCC78 |
| |
貨物編碼 | BFN60808857 | ||
產品規(guī)格 | T25培養(yǎng)瓶x1 | 1.5ml凍存管x2 | |
細胞數量 | 1x10^6 | 1x10^6 | |
保存溫度 | 37℃ | -198℃ | |
運輸方式 | 常溫保溫運輸 | 干冰運輸 | |
安全等級 | 1 | ||
用途限制 | 僅供科研 2類 | ||
培養(yǎng)體系 | 90%DMEM+10%FBS+1%三抗 | ||
培養(yǎng)溫度 | 37℃ | 二氧化碳濃度 | 5% |
簡介 | 人肺腺癌細胞HCC78取自65歲男性，該細胞源于DSMZ。 | ||
注釋 | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: MD Anderson Cell Lines Project. Doubling time: ~60-70 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis. Miscellaneous: Direct author submission of STR profile from Girard L. and Gazdar A.F. | ||
基因突變 | SLC34A2-ROS1 gene fusion (PubMed=18083107; PubMed=25485619). Homozygous for CDKN2A p.Arg58Ter (c.172C>T) (p.Pro72Leu; c.215C>T) (ClinVar=VCV000376310) (CCLE). Homozygous for TP53 p.Ser241Phe (c.722C>T) (ClinVar=VCV000012359) (CCLE; Cosmic-CLP). | ||
HLA信息 |
| ||
STR信息 |
Amelogenin X,Y CSF1PO 11,12 D1S1656 15.3,17.3 D2S441 11,14 D2S1338 17,21 D3S1358 16,17 D5S818 11,12 D7S820 9 D8S1179 13,14 D10S1248 14,16 D12S391 19,21 D13S317 8,12 D16S539 11,13 D18S51 12,16 D19S433 16,16.2 D21S11 29,30 D22S1045 15,16 DYS391 12 FGA 21,22 Penta D 7,11 Penta E 11,12 TH01 7,9.3 TPOX 8,11 vWA 15,18 | ||
參考文獻 | PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H. Characterization of human cancer cell lines by reverse-phase protein arrays. Cancer Cell 31:225-239(2017)
PubMed=30038707; DOI=10.18632/oncotarget.25642 Du L., Zhao Z., Suraokar M., Shelton S.S., Ma X., Hsiao T.-H., Minna J.D., Wistuba I., Pertsemlidis A. LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget 9:29601-29618(2018)
PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A. An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines. Cancer Res. 79:1263-1273(2019)
PubMed=31068700; DOI=10.1038/s41586-019-1186-3 Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569:503-508(2019) | ||
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